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California Reports First Clade I Mpox Case; CDPH Urges JYNNEOS Vaccination

Wednesday, November 11, 2026 · California · GSM News

The California Department of Public Health (CDPH), in news release NR26-015, confirmed the first Clade I mpox case in San Francisco and urged eligible residents to complete the two-dose JYNNEOS vaccine series. It is the seventh Clade I mpox case identified in California since November 2024.

CDPH said the patient, who was unvaccinated, is a close contact of an international traveler and is hospitalized and improving. Meanwhile, Clade II mpox cases are rising in California, averaging 14.5 cases per week in 2026, up from 5.8 in 2024 and 3.4 in 2025, with most patients unvaccinated.

Dr. Erica Pan, CDPH Director and State Public Health Officer, said vaccination remains the most effective way to prevent severe mpox illness. CDPH recommends two doses of JYNNEOS for people at risk, does not currently recommend booster doses, and advises anyone with symptoms such as a rash to seek care promptly and avoid close contact with others.

(Source: California Department of Public Health)

Source: California Department of Public Health

Published by GSM · USA (original Chinese edition)

Photo: MVA-BN(JYNNEOS)疫苗,Wikimedia Commons,Doc James,CC BY-SA 4.0 / MVA-BN (JYNNEOS) vaccine, Wikimedia Commons, Doc James, CC BY-SA 4.0

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