ꯁꯦꯂꯛꯌꯨꯏꯇꯤ ꯔꯤꯄꯣꯔꯇꯁꯤꯡ ꯚꯤꯛꯇꯣꯔꯤꯌꯥ-꯱ ꯑꯄꯗꯦꯠ: ꯒꯦꯗꯥꯇꯣꯂꯤꯁꯤꯕꯅꯥ ꯂꯤꯚꯔ ꯃꯦꯇꯥꯁ꯭ꯇꯦꯖ ꯂꯩꯇꯕꯥ ꯕ꯭ꯔꯦꯁ꯭ꯠ ꯀꯦꯟꯁꯔ ꯄꯦꯁꯦꯟꯇꯁꯤꯡꯗꯥ ꯊꯥ ꯲꯱.꯵ꯒꯤ ꯃꯦꯗꯤꯌꯝ ꯄꯤ.ꯑꯦꯐ.ꯑꯦꯁ
ꯃꯤꯅꯤꯌꯥꯄꯣꯂꯤꯁ — ꯁꯦꯂꯛꯌꯨꯏꯇꯤ ꯏꯟꯀ.(ꯅꯥꯁꯗꯥꯛ: ꯁꯤ.ꯏ.ꯑꯦꯜ.ꯁꯤ.)ꯅꯥ ꯑꯣꯛꯇꯣꯕꯔ ꯲꯴ꯗꯥ ꯌꯨꯔꯣꯄꯤꯌꯟ ꯁꯣꯁꯥꯏꯇꯤ ꯐꯣꯔ ꯃꯦꯗꯤꯀꯦꯜ ꯑꯣꯟꯀꯣꯂꯣꯖꯤ (ꯏ.ꯑꯦꯁ.ꯑꯦꯝ.ꯑꯣ.) ꯀꯪꯒ꯭ꯔꯦꯁ ꯲꯰꯲꯶ꯇꯥ ꯐꯦꯖ ꯳ ꯚꯤꯛꯇꯣꯔꯤꯌꯥ-꯱ ꯇ꯭ꯔꯥꯏꯑꯦꯂꯒꯤ ꯁ꯭ꯇꯗꯤ ꯲ꯗꯒꯤ ꯑꯅꯧꯕꯥ ꯁꯕꯒ꯭ꯔꯨꯞ ꯑꯦꯅꯥꯂꯥꯏꯁꯤꯁꯁꯤꯡ ꯄꯤꯈꯤ꯫ ꯃꯦꯇꯥꯁ꯭ꯇꯦꯖꯁꯤꯡ, ꯒꯦꯗꯥꯇꯣꯂꯤꯁꯤꯕ ꯇ꯭ꯔꯤꯄꯂꯦꯠ (ꯒꯦꯗꯥꯇꯣꯂꯤꯁꯤꯕ ꯄ꯭ꯂꯥꯁ ꯐꯨꯂꯚꯦꯁ꯭ꯠꯔꯦꯟꯇ ꯑꯃꯁꯨꯡ ꯄꯥꯂꯕꯣꯁꯤꯛꯂꯤꯕ)ꯅꯥ ꯊꯥ ꯲꯱.꯵ꯒꯤ ꯃꯦꯗꯤꯌꯝ ꯄ꯭ꯔꯣꯒ꯭ꯔꯦꯁꯟ-ꯐ꯭ꯔꯤ ꯁꯔꯚꯥꯏꯚꯜ ꯄꯨꯊꯣꯀꯈꯤ, ꯃꯁꯤ ꯑꯂꯄꯦꯂꯤꯁꯤꯕ ꯄ꯭ꯂꯥꯁ ꯐꯨꯂꯚꯦꯁ꯭ꯠꯔꯦꯟꯇꯀꯤ ꯑꯣꯏꯅꯥ ꯊꯥ ꯹.꯱ ꯑꯣꯏꯈꯤ, ꯃꯁꯤꯅꯥ ꯍꯦꯖꯥꯔꯗ ꯔꯦꯁꯤꯑꯣ ꯰.꯴꯶ (ꯄꯤ=꯰.꯰꯰꯱꯶) ꯑꯣꯏꯈꯤ꯫
ꯗꯦꯇꯥ ꯑꯁꯤ ꯒꯨꯁ꯭ꯇꯥꯚ ꯔꯧꯁꯤꯗꯥ ꯂꯩꯕꯥ ꯕ꯭ꯔꯦꯁ꯭ꯠ ꯀꯦꯟꯁꯔ ꯌꯨꯅꯤꯠꯀꯤ ꯃꯀꯣꯛ ꯗꯣꯛꯇꯔ ꯕꯥꯔꯕꯥꯔꯥ ꯄꯤꯁ꯭ꯇꯤꯂꯤꯅꯥ ꯂꯦꯞꯇꯅꯥ ꯕ꯭ꯔꯦꯀꯤꯡ ꯔꯦꯄꯤꯗ ꯑꯣꯔꯦꯜ ꯄ꯭ꯔꯖꯦꯟꯇꯦꯁꯟ (ꯑꯦꯜ.ꯕꯤ.ꯑꯦ. ꯱꯶) ꯑꯃꯗꯥ ꯄꯤꯈꯤ꯫ ꯂꯤꯚꯔ ꯃꯦꯇꯥꯁ꯭ꯇꯦꯖ ꯂꯩꯕꯥ ꯄꯦꯁꯦꯟꯇꯁꯤꯡꯒꯤ ꯃꯔꯛꯇꯥ, ꯃꯦꯗꯤꯌꯝ ꯄ꯭ꯔꯣꯒ꯭ꯔꯦꯁꯟ-ꯐ꯭ꯔꯤ ꯁꯔꯚꯥꯏꯚꯜ ꯑꯁꯤ ꯇ꯭ꯔꯤꯄꯂꯦꯠꯇꯥ ꯊꯥ 9.1 ꯑꯣꯏꯈꯤ ꯑꯃꯁꯨꯡ ꯀꯟꯠꯔꯣꯜ ꯔꯦꯖꯤꯃꯦꯟꯗꯥ ꯊꯥ 4.6 ꯑꯣꯏꯈꯤ (ꯍꯦꯖꯥꯔꯗ ꯔꯦꯁꯤꯑꯣ 0.47, p<0.0001); ꯚꯤꯁꯦꯔꯦꯜ ꯃꯦꯇꯥꯁ꯭ꯇꯦꯖ ꯂꯩꯕꯥ ꯑꯅꯥꯕꯁꯤꯡꯒꯤ ꯃꯔꯛꯇꯥ ꯃꯁꯤ ꯊꯥ ꯵.꯶ (ꯍꯦꯖꯥꯔꯗ ꯔꯦꯁꯤꯑꯣ ꯰.꯵꯲)ꯒꯥ ꯆꯥꯡꯗꯝꯅꯕꯗꯥ ꯹.꯸ ꯑꯣꯏꯈꯤ꯫ ꯄꯤ.ꯑꯥꯏ.ꯀꯦ.꯳ꯁꯤ.ꯑꯦ.-ꯃ꯭ꯌꯨꯇꯦꯟꯇ ꯀꯣꯍꯣꯔꯠꯇꯥ ꯏꯚꯥꯂꯨꯑꯦꯕꯜ ꯑꯣꯏꯕꯥ ꯑꯅꯥꯕꯁꯤꯡꯗꯥ, ꯇ꯭ꯔꯤꯄꯂꯦꯠꯀꯤ ꯑꯣꯕꯖꯦꯛꯇꯤꯕ ꯔꯦꯁ꯭ꯄꯣꯟꯁ ꯔꯦꯠ ꯑꯁꯤ ꯆꯥꯗꯥ ꯵꯹ ꯑꯣꯏꯈꯤ ꯑꯃꯁꯨꯡ ꯔꯦꯁ꯭ꯄꯣꯟꯁꯀꯤ ꯃꯦꯗꯤꯌꯝ ꯗ꯭ꯌꯨꯔꯦꯁꯟ ꯑꯁꯤ ꯊꯥ ꯱꯹.꯴ ꯑꯣꯏꯈꯤ, ꯃꯁꯤ ꯀꯟꯠꯔꯣꯂꯒꯤ ꯑꯣꯏꯅꯥ ꯆꯥꯗꯥ ꯳꯳ ꯑꯃꯁꯨꯡ ꯊꯥ ꯷.꯵ ꯑꯣꯏꯈꯤ꯫
ꯁꯦꯐꯇꯤꯒꯤ ꯃꯇꯥꯡꯗꯥ, ꯃ꯭ꯌꯨꯇꯦꯟꯇ ꯀꯣꯍꯣꯔꯠꯇꯥ ꯂꯥꯌꯦꯡꯕꯗꯥ ꯊꯣꯀꯄꯥ ꯑꯁꯣꯛ-ꯑꯄꯅꯁꯤꯡꯅꯥ ꯃꯔꯝ ꯑꯣꯏꯗꯨꯅꯥ ꯒꯦꯗꯥꯇꯣꯂꯤꯁꯤꯕ ꯊꯥꯗꯣꯀꯄꯥ ꯑꯁꯤ ꯇ꯭ꯔꯤꯄꯂꯦꯠꯀꯤ ꯑꯣꯏꯅꯥ ꯆꯥꯗꯥ ꯵ ꯑꯃꯁꯨꯡ ꯗꯕꯂꯦꯠꯀꯤ ꯑꯣꯏꯅꯥ ꯆꯥꯗꯥ ꯴ ꯑꯣꯏꯈꯤ, ꯃꯁꯤ ꯑꯂꯄꯦꯂꯤꯁꯤꯕꯀꯤ ꯑꯣꯏꯅꯥ ꯆꯥꯗꯥ ꯱꯹ ꯑꯣꯏꯈꯤ꯫ ꯀꯝꯄꯦꯅꯤ ꯑꯁꯤꯅꯥ ꯍꯥꯌꯈꯤ ꯃꯗꯨꯗꯤ ꯒꯦꯗꯥꯇꯣꯂꯤꯁꯤꯕꯀꯥ ꯂꯣꯌꯅꯅꯥ ꯒ꯭ꯔꯦꯗ ꯳ꯒꯤ ꯁ꯭ꯇꯣꯃꯥꯇꯤꯇꯤꯁ ꯑꯁꯤ ꯇ꯭ꯔꯥꯟꯁꯤꯑꯦꯟꯇ ꯑꯣꯏꯈꯤ, ꯑꯅꯤꯁꯨꯕꯥ ꯂꯥꯌꯦꯡꯕꯒꯤ ꯆꯌꯣꯜ ꯐꯥꯑꯣꯕꯗꯥ ꯆꯥꯗꯥ ꯳ꯒꯤ ꯃꯈꯥꯗꯥ ꯂꯩꯈꯤ, ꯑꯃꯁꯨꯡ ꯁ꯭ꯇꯣꯃꯥꯇꯤꯇꯤꯁꯅꯥ ꯃꯔꯝ ꯑꯣꯏꯗꯨꯅꯥ ꯂꯦꯄꯈꯤꯕꯥ ꯑꯁꯤ ꯇ꯭ꯔꯤꯄꯜ ꯑꯃꯁꯨꯡ ꯗꯕꯂꯦꯠꯀꯤ ꯑꯣꯏꯅꯥ ꯆꯥꯗꯥ ꯱ ꯑꯃꯁꯨꯡ ꯆꯥꯗꯥ ꯰ ꯑꯣꯏꯈꯤ꯫
ꯁꯦꯂꯀꯨꯏꯇꯤꯒꯤ ꯆꯤꯐ ꯃꯦꯗꯤꯀꯦꯜ ꯑꯣꯐꯤꯁꯔ ꯏꯒꯣꯔ ꯒꯣꯔꯕꯥꯆꯦꯚꯁ꯭ꯀꯤꯅꯥ ꯍꯥꯌꯈꯤ, “ꯚꯤꯛꯇꯣꯔꯤꯌꯥ-꯱ꯒꯤ ꯁ꯭ꯇꯗꯤ ꯲ꯗꯒꯤ ꯑꯍꯦꯅꯕꯥ ꯗꯦꯇꯥ ꯑꯁꯤꯅꯥ ꯒꯦꯗꯥꯇꯣꯂꯤꯁꯤꯕ ꯔꯦꯖꯤꯃꯦꯟꯗꯥ ꯂꯥꯌꯦꯡꯂꯤꯕꯥ ꯕ꯭ꯔꯦꯁ꯭ꯠ ꯀꯦꯟꯁꯔ ꯑꯅꯥꯕꯁꯤꯡꯒꯤ ꯃꯔꯨꯑꯣꯏꯕꯥ ꯁꯕ-ꯒ꯭ꯔꯨꯄꯁꯤꯡꯒꯤꯗꯃꯛꯇꯥ ꯂꯦꯞꯇꯅꯥ ꯑꯃꯁꯨꯡ ꯃꯔꯨ ꯑꯣꯏꯕꯥ ꯀ꯭ꯂꯤꯅꯤꯀꯦꯜ ꯀꯥꯟꯅꯕꯥ ꯎꯠꯂꯤ” ꯑꯃꯁꯨꯡ ꯂꯤꯚꯔ ꯃꯦꯇꯥꯁ꯭ꯇꯦꯖ ꯂꯩꯇꯕꯥ ꯑꯅꯥꯕꯁꯤꯡꯅꯥ ꯁꯦꯇꯤꯡ ꯑꯁꯤꯗꯥ ꯂꯥꯌꯦꯡꯂꯤꯕꯥ ꯑꯅꯥꯕꯥ ꯄꯨꯝꯅꯃꯛꯀꯤ ꯆꯥꯎꯔꯥꯛꯅꯥ ꯆꯥꯗꯥ ꯶꯰ꯗꯒꯤ ꯷꯰ ꯐꯥꯑꯣꯕꯥ ꯔꯤꯞꯔꯖꯦꯟꯇ ꯇꯧꯔꯤ ꯍꯥꯌꯅꯥ ꯐꯣꯡꯗꯣꯀꯈꯤ꯫ ꯃꯍꯥꯛꯅꯥ ꯍꯥꯌꯈꯤ꯫
REVTORPYK ꯍꯥꯌꯅꯥ ꯃꯥꯔꯀꯦꯇꯤꯡ ꯇꯧꯔꯤꯕꯥ ꯒꯦꯗꯥꯇꯣꯂꯤꯁꯤꯕ ꯑꯁꯤ ꯃꯦꯇꯥꯁ꯭ꯇꯦꯇꯤꯛ ꯁꯦꯇꯤꯡꯗꯥ ꯑꯦꯟꯗꯣꯛꯔꯥꯏꯟ ꯊꯦꯔꯥꯄꯤꯗꯥ ꯅꯠꯠꯔꯒꯥ ꯃꯇꯨꯡꯗꯥ ꯄ꯭ꯔꯣꯒ꯭ꯔꯦꯁ ꯇꯧꯔꯕꯥ ꯃꯇꯨꯡꯗꯥ, PIK3CA ꯃ꯭ꯌꯨꯇꯦꯁꯟ ꯂꯩꯇꯕꯥ ꯑꯅꯥꯕꯁꯤꯡꯒꯤꯗꯃꯛꯇꯥ ꯌꯨ.ꯑꯦꯁ.ꯀꯤ ꯐꯨꯗ ꯑꯃꯁꯨꯡ ꯗ꯭ꯔꯒ ꯑꯦꯗꯃꯤꯅꯤꯁ꯭ꯠꯔꯦꯁꯟ (FDA)ꯅꯥ ꯑꯌꯥꯕꯥ ꯄꯤꯕꯥ ꯄꯥꯟ-ꯄꯤ.ꯑꯥꯏ.꯳ꯀꯦ. ꯑꯅꯧꯕꯥ ꯔꯤꯖꯜꯇꯁꯤꯡ ꯑꯁꯤ ꯇꯣꯉꯥꯅꯕꯥ ꯄꯤ.ꯑꯥꯏ.ꯀꯦ.꯳ꯁꯤ.ꯑꯦ.-ꯃ꯭ꯌꯨꯇꯦꯟꯇ ꯀꯣꯍꯣꯔꯇꯀꯥ ꯃꯔꯤ ꯂꯩꯅꯩ꯫ HR+/HER2- ꯑꯁꯤ ꯈ꯭ꯕꯥꯏꯗꯒꯤ ꯀꯃꯟ ꯑꯣꯏꯕꯥ ꯕ꯭ꯔꯦꯁ꯭ꯠ ꯀꯦꯟꯁꯔ ꯁꯕꯇꯥꯏꯄꯅꯤ, ꯃꯁꯤꯅꯥ ꯆꯥꯎꯔꯥꯛꯅꯥ ꯀꯦꯁ ꯆꯥꯗꯥ 70 ꯔꯣꯝ ꯑꯣꯏꯍꯜꯂꯤ꯫ ꯃꯤꯅꯤꯌꯥꯄꯣꯂꯤꯁꯇꯥ ꯍꯦꯗꯛꯕꯥꯇꯔ ꯂꯩꯕꯥ ꯁꯦꯂꯀꯨꯏꯇꯤꯅꯥ ꯑꯍꯣꯡꯕꯥ ꯂꯥꯌꯅꯥꯒꯤ ꯑꯍꯥꯅꯕꯥ ꯂꯥꯏꯌꯦꯡ ꯑꯣꯏꯅꯥ ꯒꯦꯗꯥꯇꯣꯂꯤꯁꯤꯕ ꯔꯦꯖꯤꯃꯦꯅꯁꯤꯡꯒꯤ ꯐꯦꯖ ꯳ ꯚꯤꯛꯇꯣꯔꯤꯌꯥ-꯲ ꯇ꯭ꯔꯥꯏꯑꯦꯂꯁꯨ ꯆꯠꯊꯔꯤ꯫
Daaih Dieh: GSM · United States (English edition · Zinh Ndaangc Chinese edition)
Yaangh: 图：实验室研究人员进行样本处理（资料图）。照片：美国疾控中心（CDC），公共领域，经 Wikimedia Commons。 / Photo: A researcher at work in a laboratory (file photo). Photo by the U.S. Centers for Disease Control and Prevention, public domain, via Wikimedia Commons.
