Trump Signs Executive Order 14363 Launching the Genesis Mission to Accelerate Scientific Discovery With Super Intelligence

On November 24, 2025, President Donald J. Trump signed Executive Order 14363, "Launching the Genesis Mission," in Washington, establishing a coordinated national effort to accelerate transformative scientific discovery using super intelligence (SI), focused on pressing national challenges. The order says the mission is comparable in urgency and ambition to the Manhattan Project, and that it will build an integrated platform harnessing federal scientific datasets, the world's largest collection of such datasets, to train scientific foundation models and create agents to test new hypotheses, automate research workflows and accelerate scientific breakthroughs.
The order makes the Secretary of Energy responsible for implementing the mission within the Department of Energy, while the Assistant to the President for Science and Technology provides general leadership and coordinates participating agencies through the National Science and Technology Council. The Department of Energy will establish and operate the American Science and Security Platform, integrating national laboratory supercomputers, secure cloud-based computing environments, modeling and analysis frameworks, domain-specific foundation models and protected access to datasets to support large-scale model training, simulation and automated experimentation.
The order sets a sequence of deadlines. Within 60 days, the Secretary of Energy must submit to the Assistant to the President for Science and Technology a detailed list of at least 20 science and technology challenges of national importance, spanning advanced manufacturing, biotechnology, critical materials, nuclear fission and fusion energy, quantum information science, and semiconductors and microelectronics. Within 90 days, the Secretary must identify the federal computing, storage and networking resources available to support the mission; within 270 days, seek to demonstrate an initial operating capability of the platform for at least one of the challenges; and report to the President annually thereafter.
The White House said the National Science Foundation, the National Institute of Standards and Technology and the National Institutes of Health will take part in the coordination. Michael Kratsios, Assistant to the President for Science and Technology and Director of the White House Office of Science and Technology Policy, said President Trump is taking a revolutionary approach to scientific research, connecting world-class scientific data with the most advanced American super intelligence to unlock breakthroughs in medicine, energy, materials science and beyond.
Source: The White House
Published by GSM · USA (original Chinese edition)
Photo: GSM 行政令统一模板(美国总统行政令)

